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The choice highlighting the massive transfer of wealth to Spain accurately reflects one of the most significant outcomes of the Spanish Conquest of the Americas. Following the conquest, vast quantities of precious metals, particularly gold and silver, were extracted from the mines of the New World and shipped back to Spain. This influx of wealth significantly enriched the Spanish crown and enabled Spain to establish itself as a dominant power in Europe during the 16th and 17th centuries.

The economic implications of this wealth were profound, leading to increased military and political power for Spain, as well as a shift in trade dynamics globally. Spain’s wealth fostered further exploration and conquests in other regions, expanding their empire even further.

In contrast, the other options do not accurately represent the major consequences of the Spanish Conquest. Restoration of indigenous political systems, an increase in indigenous autonomy, and immediate cultural prosperity among native groups did not occur; rather, the conquest often led to the dismantling of existing political structures and a significant decline in indigenous populations due to violence and disease.