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Interjections are words or phrases used to express strong emotions or sudden bursts of feeling. They are often standalone or can be integrated into sentences, but when they are used in isolation to convey emotion, they are typically followed by an exclamation point to emphasize the intensity of the feeling. For instance, an interjection like "Wow!" would showcase excitement and is followed by an exclamation point.

When interjections appear in more subdued contexts or as part of a sentence, they may be followed by a comma. For example, in the sentence "Oh, I didn't see you there," the interjection "Oh" is followed by a comma to connect it to the rest of the sentence while still conveying the suddenness of the emotion. Thus, both punctuation marks—a comma and an exclamation point—are commonly used with interjections, making this the correct choice.

Options that suggest a period, question mark, or semicolon do not conventionally follow interjections, as these punctuation marks serve different grammatical purposes or are used in different contexts. This reinforces why the correct choice involving exclamation points or commas is appropriate for interjections.